SEGA Mega Drive Collection features over 30 titles including, Shinobi III, Altered Beast, Sonic The Hedgehog, Phantasy Star, and the original SEGA Mega Drive version of Golden Axe. The games in the collection have been reproduced with the utmost accuracy to the originals as possible. SEGA Mega Drive Collection also features numerous unlockable items that delve into the soul of the Mega Drive, including interviews with the original developers that created the games featured in the collection, a museum area with interesting facts about the games, a hint area to help gamers complete their favourite SEGA Mega Drive games, and SEGA arcade games from the Mega Drive era.

• 1. Alex Kidd In The Enchanted Castle
• 2. Altered Beast
• 3. Bonanza Bros.
• 4. Columns
• 5. Comix Zone
• 6. Decap Attack starring Chuck D. Head
• 7. Ecco the Dolphin
• 8. Ecco II: The Tides of Time
• 9. Ecco Jr.
• 10. Kid Chameleon
• 11. Flicky
• 12. Gain Ground
• 13. Golden Axe I
• 14. Golden Axe II
• 15. Golden Axe III
• 16. Phantasy Star II
• 17. Phantasy Star III: Generations of Doom
• 18. Phantasy Star IV: The End of the Millenium
• 19. Ristar
• 20. Shinobi III: Return of the Ninja Master
• 21. Sonic the Hedgehog
• 22. Sonic the Hedgehog 2
• 23. Super Thunder Blade
• 24. Sword of Vermilion
• 25. VectorMan
• 26. VectorMan 2
• 27. Virtua Fighter 2
• And even more to unlock!